Keyword Index

A

  • A549 cell line Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
  • Acetaminophen Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
  • Acupoint catgut embedding Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
  • Acute Kidney Injuries Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
  • Acute kidney injury N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
  • Acute lung injury Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
  • Acute lung injury Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
  • Acute lymphoblastic - leukemia (ALL) Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
  • Acute pancreatitis Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
  • Adriamycin Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
  • ADSCs Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
  • Age-related macular - degeneration Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
  • Aging Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
  • Aging Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
  • Aging 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
  • Agmatine Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
  • Akt Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
  • Akt Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
  • Alamandine Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
  • Alginate hydrogel Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
  • Alpha-mangostin Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
  • Alpha-pinene Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
  • Alveolar epithelial cell Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
  • Alzheimer disease Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
  • AM251 Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
  • Amiodarone How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
  • AMP-activated protein - kinase Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
  • Amyloid-beta Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
  • Angiotensin II Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
  • Animal model Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
  • Annulus fibrosus Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
  • Antibacterial agents Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
  • Antibacterial drug resistance Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
  • Antibiotic resistance Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
  • Anti-cancer Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
  • Antihemophilic factor Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
  • Anti-inflammation Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
  • Anti-inflammatory Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
  • Anti-inflammatory Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
  • Anti-inflammatory agents Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
  • Anti-metastatic activity In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
  • Antimicrobial agent Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
  • Antiobesity Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
  • Anti-oxidant Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
  • Anti-oxidant Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
  • Antioxidants Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
  • Anti-Oxidants Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
  • Anti-Oxidants Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
  • Anti-Oxidants Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
  • Anti-Oxidants Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
  • Anti-oxidative Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
  • Anxiety Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
  • Apigenin Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
  • Apoptosis Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
  • Apoptosis Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
  • Apoptosis Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
  • Apoptosis Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
  • Apoptosis Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
  • Apoptosis Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
  • Apoptosis Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
  • Apoptosis Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
  • Apoptosis Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
  • Apoptosis 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
  • Apoptosis Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
  • Apoptosis Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
  • Apoptosis N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
  • Apoptosis Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
  • Apoptosis Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
  • Apoptosis Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
  • Apoptosis-inducing factor Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
  • Apoptotic activity In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
  • Arterial Pressure Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
  • ATG4B Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
  • Atherosclerosis Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
  • Atrial fibrillation Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
  • Atrial fibrosis Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
  • Auditory dysfunction Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
  • Autism Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
  • Autophagy Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
  • Autophagy Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
  • Autophagy Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
  • Autophagy Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
  • Autophagy THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
  • Autophagy Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
  • Autophagy Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
  • Autophagy Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
  • Autophagy Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
  • Azithromycin Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]

B

  • Beclin 1 Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
  • Behavior Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
  • Bentonite-nanoparticles Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
  • Bevacizumab Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
  • Biofilm Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
  • Bioinformatics Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
  • Bioinformatics analysis Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
  • Blood urea nitrogen Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
  • Body mass index Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
  • Bone Density Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
  • Box-Behnken design Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
  • Brain Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
  • Brain Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
  • Brain edema Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
  • Brain injury Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
  • Brain injury Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
  • Brain ischemia Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
  • Breast Cancer Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
  • Broccoli Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]

C

  • Cadmium Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
  • Cancer-selective-cytotoxicity In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
  • Cancer Treatment Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
  • Cannabinoid receptors Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
  • Cannabinoids Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
  • Cardiac fibroblast SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
  • Cardiac fibrosis SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
  • Cardiac remodeling Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
  • Cardiomyocytes Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
  • Cardiotoxicity Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
  • Cardiovascular Disease Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
  • Carotenoids Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
  • Caspases Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
  • Catechol-O-methyltransferase (COMT) H9C2 A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]
  • Cation channels Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
  • Cecal ligation and puncture Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
  • Cell damage Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
  • Cell death Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
  • Cell wall Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
  • Cetirizine Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
  • Chemosensitivity Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
  • Chitosan Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
  • Chitosan Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
  • Chronic pain Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
  • Cited2 Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
  • Collagen I SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
  • Collagen III SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
  • Colorectal cancer Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
  • Combination therapy Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
  • Computational biology Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
  • Conditioned medium Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
  • Core/shell nanofiber Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
  • Corilagin Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
  • Costunolide Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
  • COVID-19 Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
  • Creatinine Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
  • Creatinine Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
  • CREB/BDNF Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
  • Crocetin An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
  • Crocin Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
  • Crocin An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
  • Crocin Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
  • Crocin Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
  • Crocus sativus An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
  • Crocus sativus Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
  • Cyclophosphamide Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
  • Cytokine Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]

D

  • Dexmedetomidine Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
  • Dexpanthenol Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
  • Diabetes Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
  • Diabetes Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
  • Diabetes Mellitus Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
  • Diabetes mellitus type 1 Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
  • Diabetic nephropathy Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
  • Diabetic nephropathy Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
  • Diabetic peripheral- neuropathy Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
  • Diets Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
  • Diosmin Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
  • Direct current Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
  • DNA Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
  • DNA damage Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
  • D-Pinitol D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
  • Drug discovery Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
  • Drug resistance Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
  • Drug resistance Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
  • Dyslipidemia Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]

E

  • Electroacupuncture Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
  • Electroacupuncture Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
  • Electrocardiography Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
  • Embryo development All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
  • Endoplasmic reticulum - stress Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
  • Endoplasmic reticulum - stress Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
  • Endoplasmic reticulum- stress Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
  • Endoplasmic reticulum-stress Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
  • Endothelial cells Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
  • Epigenomics Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
  • ER stress Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
  • Erythropoietin Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
  • Exosome Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
  • Exosomes Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]

F

  • Febuxostat Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
  • FeONPs-Cur Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
  • Fertility agents All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
  • Fibroblast Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
  • Fibromyalgia Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
  • Fibrosis Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
  • Fluorescent light intensity Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
  • Fluorouracil THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
  • Food additives Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
  • Fucoidan Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]

G

  • Gabapentin Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
  • GABARAPL1 Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
  • Garcinia mangostana Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
  • Gender Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
  • Gene delivery Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
  • Glioblastoma Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
  • Glutamatergic transmission Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
  • Glutathione Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
  • Glutathione Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
  • Glycerol Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
  • Glycogen synthase kinase 3 beta Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
  • Gold colloid Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
  • Growth differentiation-factor 15 Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
  • Growth Factor All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]

H

  • Haemophilia therapy Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
  • Handle region peptide Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
  • Harmaline-ag containing- folate-linked chitosan-nanoparticles (HA-fCNP) In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
  • Heart protection Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
  • Heart rate Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
  • Hemophilia A Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
  • Hepatocellular carcinoma Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
  • Hepatoprotection Inflammation Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
  • HepG2 Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
  • High cholesterol diet Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
  • Hippocampus Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
  • Hippocampus Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
  • Hippocampus Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
  • Histone deacetylase- inhibitors Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
  • Histopathology Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
  • HMGB1/NF-κB signaling - pathway Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
  • HOMA-IR Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
  • HspX/EsxS Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
  • HTR-8/SVneo cells Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
  • Human THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
  • HUVEC Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
  • Hyperglycemia Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
  • Hyperglycemia Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
  • Hyperlipidemia Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
  • Hypertension Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
  • Hypertension Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
  • Hypoxia-induced pulmonary hypertension Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
  • Hypoxia inducible factor Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
  • Hypoxia-inducible factor-1 Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]

I

  • Immflamation Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
  • Immune Infiltrates Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
  • Immune system Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
  • Immunotherapy Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
  • Implant Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
  • Inflammation Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
  • Inflammation Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
  • Inflammation Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
  • Inflammation TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
  • Inflammation D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
  • Inflammation Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
  • Inflammation Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
  • Inflammation Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
  • Inflammation Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
  • Inflammation Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
  • Inflammation Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
  • Inflammation Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
  • Inflammation Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
  • Inflammation Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
  • Inflammation Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
  • Inflammation Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
  • Inflammation Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
  • Inflammation Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
  • Injury Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
  • Interferon gamma Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
  • Intervertebral disc-degeneration Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
  • Intracerebral hemorrhage NLRP3 inflammasome Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
  • Intraperitoneal injection Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
  • In vitro oocyte maturation - techniques All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
  • Iridaceae Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
  • Ischemia TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
  • Ischemia-reperfusion Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
  • ISCOMATRIX Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
  • Isoproterenol D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]

K

  • Kidney Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
  • Kidney Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
  • Kidney Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
  • Kidney Injury Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]

L

  • Lactobacillus Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
  • Laminin Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
  • Langendorff heart Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
  • LC3 Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
  • LC-MS/MS Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
  • Lipofuscin Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
  • Lipopolysaccharide Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
  • Liposome How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
  • Liver Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
  • Liver injury Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
  • Liver injury Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
  • Long-term potentiation Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
  • Loratadine Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
  • Low-density lipoprotein Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
  • Lung Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
  • Lung cancer Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
  • Luteolin A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]

M

  • Malondialdehyde Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
  • Malondialdehyde Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
  • MAP kinase signaling - system Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
  • MAPK pathway Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
  • Medical interventionst Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
  • Melanin Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
  • Melatonin Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
  • Melatonin Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
  • Memory Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
  • Memory Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
  • Mesenchymal stem cells Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
  • Mesenchymal stem cells Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
  • Mesenchymal stem cells Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
  • Mesenchymal stem cells Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
  • Metal-organic frameworks Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
  • Metformin Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
  • Metformin Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
  • Methotrexate Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
  • Methylene blue Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
  • Methylthioninium chloride Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
  • Microbial Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
  • Microbiology Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
  • MicroRNA Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
  • Migration Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
  • Migration Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
  • MiRNA-412-5p Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
  • Mitochondria Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
  • Mitochondrial dysfunction N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
  • Mitogen-activated protein - kinase 3 Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
  • Molecular mechanism Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
  • Molecular targeted therapy Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
  • Monoamines Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
  • Monocrotaline Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
  • Monocrotaline Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
  • Motor Activity Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
  • Mouse Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
  • Mouse Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
  • MPLA Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
  • Mycobacterium tuberculosis Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
  • Mycobacterium tuberculosis Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
  • Myelin protein zero Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
  • Myocardial ischemia - reperfusion A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]
  • Myocardial ischemia/reperfusion injury Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
  • Myoglobin Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
  • Myoglobin Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]

N

  • N-acetyl cysteine Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
  • N-acetylcysteine Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
  • N-acetylcysteine N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
  • NADH oxidase Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
  • NADPH oxidase Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
  • Nalm-6 Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
  • Nanoemulsion How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
  • Nanofibrous scaffold Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
  • Nanoparticle Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
  • Nanostructures Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
  • Naringin Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
  • Nasal administration Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
  • Nasal delivery Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
  • Nasopharyngeal carcinoma Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
  • Natural products Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
  • Necroptosis Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
  • Necrosis Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
  • Necrostatin-1 Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
  • Nephrotoxicity Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
  • Nephrotoxicity 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
  • Nerve growth factor Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
  • Neurogenesis Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
  • Neuropathic pain Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
  • Neuropeptide Q Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
  • Neuroprotection Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
  • Neuroprotection D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
  • Neuroprotective Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
  • Neurosurgery Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
  • Neurotoxicity D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
  • Neurotoxicity Syndromes Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
  • NF-κB Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
  • NF-κB Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
  • Nigella Sativa Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
  • NOD mice Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
  • Non-alcoholic fatty liver disease Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
  • Non-alcoholic steatohepatitis Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
  • NOTCH Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
  • Nrf2 Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
  • Nrf2 Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
  • Nuclear factor Kappa B Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]

O

  • Obesity Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
  • Octreotide Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
  • Orexin receptors Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
  • Osteoarthritis Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
  • Osteoblast Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
  • Osteogenesis Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
  • Osteomyelitis Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
  • Osteoporosis Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
  • Oxaliplatin Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
  • Oxidative stress Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
  • Oxidative stress Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
  • Oxidative stress Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
  • Oxidative stress D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
  • Oxidative stress Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
  • Oxidative stress Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
  • Oxidative stress Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
  • Oxidative stress 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
  • Oxidative stress Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
  • Oxidative stress Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
  • Oxidative stress Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
  • Oxidative stress Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
  • Oxidative stress Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]

P

  • Pantoprazole Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
  • Paraquat Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
  • Paraquat Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
  • Parathyroid hormone Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
  • Paraventricular hypothalamic nucleus Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
  • Parkinson’s disease Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
  • PEGylated liposomes Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
  • Permeation Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
  • Pharmacokinetic parameter How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
  • Pharmacological action Saffron An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
  • Pharmacology Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
  • PI3K Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
  • PI3K Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
  • PI3K/Akt Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
  • PI3K/AKT/FOXO/PPARγ- Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
  • Pioglitazone Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
  • PLUSCOM Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
  • Polycaprolactone Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
  • Polycaprolactone Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
  • Polyethyleneimine Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
  • Polyherbal extract Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
  • Preeclampsia Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
  • Prefrontal cortex Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
  • Presbycusis Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
  • Prevention Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
  • Prevention Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
  • Probiotics Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
  • Programmed cell death Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
  • Proliferation Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
  • Propolis Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
  • Prostatic neoplasm Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
  • PTEN protein Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
  • Pulmonary Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
  • Pulmonary artery smooth muscle cells Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]

Q

  • Quality of life Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
  • Quercetin Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
  • Quercetin Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]

R

  • Rabdomyolysis Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
  • Rat Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
  • Rat Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
  • Rat Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
  • Rats Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
  • Reactive Oxygen Species TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
  • Reactive oxygen species - (ROS) Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
  • Recombinant FVIII Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
  • Release kinetics Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
  • Renin angiotensin aldosterone system Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
  • Renin–angiotensin system Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
  • Reproduction All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
  • Reproductive Hormones Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
  • Rescue therapy Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
  • Resistin Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
  • Right ventricular - hypertrophy Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
  • Rosmarinic acid Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
  • Royal jelly (RJ) Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]

S

  • Safranal An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
  • Safranal Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
  • Salidroside Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
  • Salvin Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
  • Saroglitazar Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
  • SARS-CoV-2 Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
  • Sciatic nerve Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
  • Sciatic nerve Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
  • Second brain injury Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
  • Secretome Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
  • Senescence Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
  • Sepsis Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
  • Sepsis Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
  • Sepsis N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
  • Serotype Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
  • Signaling pathway Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
  • Silymarin Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
  • SIRT1 Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
  • Sirt3 N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
  • Skin aging Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
  • Skin neoplasms Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
  • Slit guidance ligand 3 SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
  • Smad2/3 Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
  • Sodium arsenite Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
  • Sodium arsenite Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
  • Sodium dichloroacetate Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
  • Sodium iodate Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
  • Solid lipid nanoparticle How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
  • Solid lipid nanoparticle Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
  • Somatosensory cortex Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
  • Sox11 Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
  • Sperm analyses Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
  • Spermatogenesis Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
  • Spexin Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
  • Staphylococcus aureus Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
  • STAT6 Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
  • Stomach Neoplasms THADA protein THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
  • Streptococcus pneumoniae Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
  • Subchondral bone Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
  • Sulforaphane Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
  • Surface proteins Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
  • Surgery Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]

T

  • Tamoxifen Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
  • TCS OX2 29 Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
  • Testicular toxicity Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
  • Testicular toxicity Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
  • Testicular toxicity Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
  • Testis Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
  • Testis Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
  • Tetramethylpyrazine Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
  • TFAM Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
  • TGFβ Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
  • Thalamus TRPV1 Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
  • Therapeutic biomarker Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
  • Therapeutics Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
  • Therapeutic targets Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
  • Thymoquinone Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
  • Tissue engineering Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
  • Toll-like receptor-4 Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
  • Toll-like receptors Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
  • TOR Serine-Threonine- Kinases THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
  • Toxicity Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
  • Transfection Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
  • Transient receptor potential channels TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
  • Translational medicine Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
  • Transplantation Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
  • Trans-sodium crocetinate Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
  • Treatment Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
  • Trend analysis Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
  • Tropisetron 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
  • TRPA1 cation channel TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
  • Trpm Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
  • Tubal factor infertility Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
  • Tumor necrosis factors Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
  • Tumor suppressor protein p53 Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
  • Tumor suppressor protein- p53 Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
  • Type 1 diabetes Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]

U

  • U87 Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
  • UIO-66 Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
  • Ulcerative colitis Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
  • Unacylated ghrelin Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
  • Uterine Cervical Neoplasms Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]

V

  • Valproic acid Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
  • Vascular calcification Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
  • Vascular Endothelial Growth Factor Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
  • Vascular endothelial growth - factors Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
  • Vascular injuries Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
  • Vitamin B12 Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
  • Vitamin E Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
  • Voluntary exercise Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]

W

  • White Matter Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
  • WNT Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
  • Wnt5a Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
  • Wound healing Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
  • Wound healing Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]

Y

  • Young plasma Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]

Z

  • Zingerone Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]