A
-
A549 cell line
Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
-
Acetaminophen
Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
-
Acupoint catgut embedding
Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
-
Acute Kidney Injuries
Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
-
Acute kidney injury
N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
-
Acute lung injury
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
-
Acute lung injury
Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
-
Acute lymphoblastic - leukemia (ALL)
Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
-
Acute pancreatitis
Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
-
Adriamycin
Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
-
ADSCs
Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
-
Age-related macular - degeneration
Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
-
Aging
Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
-
Aging
Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
-
Aging
5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
-
Agmatine
Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
-
Akt
Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
-
Akt
Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
-
Alamandine
Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
-
Alginate hydrogel
Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
-
Alpha-mangostin
Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
-
Alpha-pinene
Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
-
Alveolar epithelial cell
Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
-
Alzheimer disease
Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
-
AM251
Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
-
Amiodarone
How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
-
AMP-activated protein - kinase
Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
-
Amyloid-beta
Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
-
Angiotensin II
Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
-
Animal model
Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
-
Annulus fibrosus
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
-
Antibacterial agents
Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
-
Antibacterial drug resistance
Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
-
Antibiotic resistance
Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
-
Anti-cancer
Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
-
Antihemophilic factor
Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
-
Anti-inflammation
Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
-
Anti-inflammatory
Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
-
Anti-inflammatory
Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
-
Anti-inflammatory agents
Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
-
Anti-metastatic activity
In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
-
Antimicrobial agent
Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
-
Antiobesity
Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
-
Anti-oxidant
Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
-
Anti-oxidant
Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
-
Antioxidants
Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
-
Anti-Oxidants
Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
-
Anti-Oxidants
Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
-
Anti-Oxidants
Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
-
Anti-Oxidants
Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
-
Anti-oxidative
Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
-
Anxiety
Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
-
Apigenin
Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
-
Apoptosis
Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
-
Apoptosis
Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
-
Apoptosis
Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
-
Apoptosis
Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
-
Apoptosis
Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
-
Apoptosis
Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
-
Apoptosis
Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
-
Apoptosis
Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
-
Apoptosis
Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
-
Apoptosis
5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
-
Apoptosis
Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
-
Apoptosis
Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
-
Apoptosis
N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
-
Apoptosis
Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
-
Apoptosis
Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
-
Apoptosis
Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
-
Apoptosis-inducing factor
Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
-
Apoptotic activity
In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
-
Arterial Pressure
Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
-
ATG4B
Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
-
Atherosclerosis
Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
-
Atrial fibrillation
Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
-
Atrial fibrosis
Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
-
Auditory dysfunction
Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
-
Autism
Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
-
Autophagy
Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
-
Autophagy
Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
-
Autophagy
Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
-
Autophagy
Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
-
Autophagy
THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
-
Autophagy
Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
-
Autophagy
Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
-
Autophagy
Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
-
Autophagy
Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
-
Azithromycin
Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
B
-
Beclin 1
Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
-
Behavior
Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
-
Bentonite-nanoparticles
Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
-
Bevacizumab
Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
-
Biofilm
Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
-
Bioinformatics
Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
-
Bioinformatics analysis
Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
-
Blood urea nitrogen
Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
-
Body mass index
Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
-
Bone Density
Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
-
Box-Behnken design
Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
-
Brain
Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
-
Brain
Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
-
Brain edema
Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
-
Brain injury
Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
-
Brain injury
Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
-
Brain ischemia
Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
-
Breast Cancer
Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
-
Broccoli
Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
C
-
Cadmium
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
-
Cancer-selective-cytotoxicity
In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
-
Cancer Treatment
Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
-
Cannabinoid receptors
Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
-
Cannabinoids
Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
-
Cardiac fibroblast
SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
-
Cardiac fibrosis
SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
-
Cardiac remodeling
Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
-
Cardiomyocytes
Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
-
Cardiotoxicity
Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
-
Cardiovascular Disease
Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
-
Carotenoids
Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
-
Caspases
Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
-
Catechol-O-methyltransferase (COMT) H9C2
A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]
-
Cation channels
Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
-
Cecal ligation and puncture
Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
-
Cell damage
Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
-
Cell death
Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
-
Cell wall
Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
-
Cetirizine
Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
-
Chemosensitivity
Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
-
Chitosan
Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
-
Chitosan
Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
-
Chronic pain
Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
-
Cited2
Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
-
Collagen I
SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
-
Collagen III
SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
-
Colorectal cancer
Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
-
Combination therapy
Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
-
Computational biology
Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
-
Conditioned medium
Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
-
Core/shell nanofiber
Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
-
Corilagin
Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
-
Costunolide
Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
-
COVID-19
Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
-
Creatinine
Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
-
Creatinine
Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
-
CREB/BDNF
Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
-
Crocetin
An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
-
Crocin
Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
-
Crocin
An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
-
Crocin
Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
-
Crocin
Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
-
Crocus sativus
An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
-
Crocus sativus
Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
-
Cyclophosphamide
Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
-
Cytokine
Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
D
-
Dexmedetomidine
Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
-
Dexpanthenol
Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
-
Diabetes
Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
-
Diabetes
Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
-
Diabetes Mellitus
Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
-
Diabetes mellitus type 1
Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
-
Diabetic nephropathy
Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
-
Diabetic nephropathy
Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
-
Diabetic peripheral- neuropathy
Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
-
Diets
Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
-
Diosmin
Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
-
Direct current
Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
-
DNA
Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
-
DNA damage
Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
-
D-Pinitol
D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
-
Drug discovery
Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
-
Drug resistance
Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
-
Drug resistance
Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
-
Dyslipidemia
Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
E
-
Electroacupuncture
Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
-
Electroacupuncture
Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
-
Electrocardiography
Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
-
Embryo development
All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
-
Endoplasmic reticulum - stress
Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
-
Endoplasmic reticulum - stress
Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
-
Endoplasmic reticulum- stress
Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
-
Endoplasmic reticulum-stress
Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
-
Endothelial cells
Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
-
Epigenomics
Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
-
ER stress
Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
-
Erythropoietin
Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
-
Exosome
Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
-
Exosomes
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
F
-
Febuxostat
Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
-
FeONPs-Cur
Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
-
Fertility agents
All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
-
Fibroblast
Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
-
Fibromyalgia
Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
-
Fibrosis
Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
-
Fluorescent light intensity
Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
-
Fluorouracil
THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
-
Food additives
Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
-
Fucoidan
Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
G
-
Gabapentin
Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
-
GABARAPL1
Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
-
Garcinia mangostana
Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
-
Gender
Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
-
Gene delivery
Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
-
Glioblastoma
Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
-
Glutamatergic transmission
Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
-
Glutathione
Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
-
Glutathione
Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
-
Glycerol
Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
-
Glycogen synthase kinase 3 beta
Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
-
Gold colloid
Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
-
Growth differentiation-factor 15
Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
-
Growth Factor
All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
H
-
Haemophilia therapy
Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
-
Handle region peptide
Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
-
Harmaline-ag containing- folate-linked chitosan-nanoparticles (HA-fCNP)
In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
-
Heart protection
Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
-
Heart rate
Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
-
Hemophilia A
Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
-
Hepatocellular carcinoma
Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
-
Hepatoprotection Inflammation
Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
-
HepG2
Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
-
High cholesterol diet
Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
-
Hippocampus
Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
-
Hippocampus
Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
-
Hippocampus
Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
-
Histone deacetylase- inhibitors
Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
-
Histopathology
Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
-
HMGB1/NF-κB signaling - pathway
Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
-
HOMA-IR
Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
-
HspX/EsxS
Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
-
HTR-8/SVneo cells
Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
-
Human
THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
-
HUVEC
Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
-
Hyperglycemia
Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
-
Hyperglycemia
Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
-
Hyperlipidemia
Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
-
Hypertension
Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
-
Hypertension
Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
-
Hypoxia-induced pulmonary hypertension
Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
-
Hypoxia inducible factor
Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
-
Hypoxia-inducible factor-1
Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
I
-
Immflamation
Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
-
Immune Infiltrates
Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
-
Immune system
Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
-
Immunotherapy
Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
-
Implant
Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
-
Inflammation
Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
-
Inflammation
Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
-
Inflammation
Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
-
Inflammation
TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
-
Inflammation
D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
-
Inflammation
Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
-
Inflammation
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
-
Inflammation
Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
-
Inflammation
Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
-
Inflammation
Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
-
Inflammation
Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
-
Inflammation
Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
-
Inflammation
Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
-
Inflammation
Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
-
Inflammation
Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
-
Inflammation
Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
-
Inflammation
Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
-
Inflammation
Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
-
Injury
Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
-
Interferon gamma
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
-
Intervertebral disc-degeneration
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
-
Intracerebral hemorrhage NLRP3 inflammasome
Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
-
Intraperitoneal injection
Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
-
In vitro oocyte maturation - techniques
All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
-
Iridaceae
Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
-
Ischemia
TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
-
Ischemia-reperfusion
Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
-
ISCOMATRIX
Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
-
Isoproterenol
D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
K
-
Kidney
Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
-
Kidney
Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
-
Kidney
Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
-
Kidney Injury
Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
L
-
Lactobacillus
Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
-
Laminin
Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
-
Langendorff heart
Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
-
LC3
Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
-
LC-MS/MS
Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
-
Lipofuscin
Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
-
Lipopolysaccharide
Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
-
Liposome
How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
-
Liver
Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
-
Liver injury
Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
-
Liver injury
Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
-
Long-term potentiation
Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
-
Loratadine
Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
-
Low-density lipoprotein
Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
-
Lung
Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
-
Lung cancer
Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
-
Luteolin
A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]
M
-
Malondialdehyde
Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
-
Malondialdehyde
Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
-
MAP kinase signaling - system
Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
-
MAPK pathway
Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
-
Medical interventionst
Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
-
Melanin
Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
-
Melatonin
Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
-
Melatonin
Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
-
Memory
Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
-
Memory
Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
-
Mesenchymal stem cells
Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
-
Mesenchymal stem cells
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
-
Mesenchymal stem cells
Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
-
Mesenchymal stem cells
Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
-
Metal-organic frameworks
Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
-
Metformin
Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
-
Metformin
Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
-
Methotrexate
Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
-
Methylene blue
Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
-
Methylthioninium chloride
Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
-
Microbial
Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
-
Microbiology
Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
-
MicroRNA
Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
-
Migration
Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
-
Migration
Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
-
MiRNA-412-5p
Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
-
Mitochondria
Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
-
Mitochondrial dysfunction
N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
-
Mitogen-activated protein - kinase 3
Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
-
Molecular mechanism
Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
-
Molecular targeted therapy
Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
-
Monoamines
Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
-
Monocrotaline
Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
-
Monocrotaline
Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
-
Motor Activity
Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
-
Mouse
Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
-
Mouse
Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
-
MPLA
Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
-
Mycobacterium tuberculosis
Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
-
Mycobacterium tuberculosis
Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
-
Myelin protein zero
Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
-
Myocardial ischemia - reperfusion
A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]
-
Myocardial ischemia/reperfusion injury
Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
-
Myoglobin
Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
-
Myoglobin
Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
N
-
N-acetyl cysteine
Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
-
N-acetylcysteine
Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
-
N-acetylcysteine
N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
-
NADH oxidase
Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
-
NADPH oxidase
Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
-
Nalm-6
Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
-
Nanoemulsion
How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
-
Nanofibrous scaffold
Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
-
Nanoparticle
Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
-
Nanostructures
Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
-
Naringin
Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
-
Nasal administration
Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
-
Nasal delivery
Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
-
Nasopharyngeal carcinoma
Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
-
Natural products
Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
-
Necroptosis
Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
-
Necrosis
Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
-
Necrostatin-1
Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
-
Nephrotoxicity
Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
-
Nephrotoxicity
5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
-
Nerve growth factor
Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
-
Neurogenesis
Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
-
Neuropathic pain
Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
-
Neuropeptide Q
Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
-
Neuroprotection
Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
-
Neuroprotection
D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
-
Neuroprotective
Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
-
Neurosurgery
Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
-
Neurotoxicity
D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
-
Neurotoxicity Syndromes
Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
-
NF-κB
Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
-
NF-κB
Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
-
Nigella Sativa
Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
-
NOD mice
Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
-
Non-alcoholic fatty liver disease
Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
-
Non-alcoholic steatohepatitis
Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
-
NOTCH
Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
-
Nrf2
Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
-
Nrf2
Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
-
Nuclear factor Kappa B
Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
O
-
Obesity
Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
-
Octreotide
Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
-
Orexin receptors
Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
-
Osteoarthritis
Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
-
Osteoblast
Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
-
Osteogenesis
Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
-
Osteomyelitis
Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
-
Osteoporosis
Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
-
Oxaliplatin
Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
-
Oxidative stress
Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
-
Oxidative stress
Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
-
Oxidative stress
Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
-
Oxidative stress
D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
-
Oxidative stress
Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
-
Oxidative stress
Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
-
Oxidative stress
Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
-
Oxidative stress
5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
-
Oxidative stress
Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inflammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
-
Oxidative stress
Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
-
Oxidative stress
Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
-
Oxidative stress
Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
-
Oxidative stress
Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
P
-
Pantoprazole
Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
-
Paraquat
Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
-
Paraquat
Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
-
Parathyroid hormone
Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
-
Paraventricular hypothalamic nucleus
Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
-
Parkinson’s disease
Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
-
PEGylated liposomes
Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
-
Permeation
Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
-
Pharmacokinetic parameter
How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
-
Pharmacological action Saffron
An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
-
Pharmacology
Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
-
PI3K
Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
-
PI3K
Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
-
PI3K/Akt
Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
-
PI3K/AKT/FOXO/PPARγ-
Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
-
Pioglitazone
Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
-
PLUSCOM
Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
-
Polycaprolactone
Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
-
Polycaprolactone
Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
-
Polyethyleneimine
Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
-
Polyherbal extract
Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
-
Preeclampsia
Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
-
Prefrontal cortex
Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
-
Presbycusis
Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
-
Prevention
Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
-
Prevention
Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
-
Probiotics
Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
-
Programmed cell death
Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
-
Proliferation
Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
-
Propolis
Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
-
Prostatic neoplasm
Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
-
PTEN protein
Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
-
Pulmonary
Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
-
Pulmonary artery smooth muscle cells
Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
Q
-
Quality of life
Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
-
Quercetin
Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
-
Quercetin
Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
R
-
Rabdomyolysis
Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
-
Rat
Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
-
Rat
Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
-
Rat
Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
-
Rats
Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
-
Reactive Oxygen Species
TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
-
Reactive oxygen species - (ROS)
Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
-
Recombinant FVIII
Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
-
Release kinetics
Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
-
Renin angiotensin aldosterone system
Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
-
Renin–angiotensin system
Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
-
Reproduction
All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
-
Reproductive Hormones
Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
-
Rescue therapy
Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
-
Resistin
Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
-
Right ventricular - hypertrophy
Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
-
Rosmarinic acid
Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
-
Royal jelly (RJ)
Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
S
-
Safranal
An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
-
Safranal
Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
-
Salidroside
Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
-
Salvin
Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
-
Saroglitazar
Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
-
SARS-CoV-2
Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
-
Sciatic nerve
Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
-
Sciatic nerve
Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
-
Second brain injury
Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
-
Secretome
Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
-
Senescence
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
-
Sepsis
Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
-
Sepsis
Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
-
Sepsis
N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
-
Serotype
Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
-
Signaling pathway
Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
-
Silymarin
Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
-
SIRT1
Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
-
Sirt3
N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
-
Skin aging
Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
-
Skin neoplasms
Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
-
Slit guidance ligand 3
SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
-
Smad2/3
Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
-
Sodium arsenite
Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
-
Sodium arsenite
Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
-
Sodium dichloroacetate
Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
-
Sodium iodate
Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
-
Solid lipid nanoparticle
How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
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Solid lipid nanoparticle
Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
-
Somatosensory cortex
Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
-
Sox11
Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
-
Sperm analyses
Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
-
Spermatogenesis
Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
-
Spexin
Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
-
Staphylococcus aureus
Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
-
STAT6
Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
-
Stomach Neoplasms THADA protein
THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
-
Streptococcus pneumoniae
Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
-
Subchondral bone
Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
-
Sulforaphane
Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
-
Surface proteins
Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
-
Surgery
Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
T
-
Tamoxifen
Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
-
TCS OX2 29
Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
-
Testicular toxicity
Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
-
Testicular toxicity
Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
-
Testicular toxicity
Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
-
Testis
Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
-
Testis
Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
-
Tetramethylpyrazine
Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
-
TFAM
Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
-
TGFβ
Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
-
Thalamus TRPV1
Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
-
Therapeutic biomarker
Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
-
Therapeutics
Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
-
Therapeutic targets
Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
-
Thymoquinone
Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
-
Tissue engineering
Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
-
Toll-like receptor-4
Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
-
Toll-like receptors
Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
-
TOR Serine-Threonine- Kinases
THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
-
Toxicity
Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
-
Transfection
Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
-
Transient receptor potential channels
TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
-
Translational medicine
Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
-
Transplantation
Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
-
Trans-sodium crocetinate
Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
-
Treatment
Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
-
Trend analysis
Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
-
Tropisetron
5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
-
TRPA1 cation channel
TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
-
Trpm
Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
-
Tubal factor infertility
Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
-
Tumor necrosis factors
Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
-
Tumor suppressor protein p53
Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
-
Tumor suppressor protein- p53
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
-
Type 1 diabetes
Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
U
-
U87
Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
-
UIO-66
Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
-
Ulcerative colitis
Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
-
Unacylated ghrelin
Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
-
Uterine Cervical Neoplasms
Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
V
-
Valproic acid
Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
-
Vascular calcification
Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
-
Vascular Endothelial Growth Factor
Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
-
Vascular endothelial growth - factors
Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
-
Vascular injuries
Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
-
Vitamin B12
Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
-
Vitamin E
Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
-
Voluntary exercise
Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
W
-
White Matter
Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
-
WNT
Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
-
Wnt5a
Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
-
Wound healing
Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
-
Wound healing
Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
Y
-
Young plasma
Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
Z
-
Zingerone
Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
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